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FETUB

Synonyms
16G2, Gugu, IRL685
External resources
Summary
The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,343
Likely benign
649
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FETUB gene.

Phenotype class
Patients in 3billion (%)

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