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ENDOG

Synonyms
-
External resources
Summary
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
7,640
Likely benign
1,372
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ENDOG gene.

Phenotype class
Patients in 3billion (%)

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