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CXCL17

Synonyms
DMC, Dcip1, UNQ473, VCC-1, VCC1
External resources
Summary
The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,624
Likely benign
879
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CXCL17 gene.

Phenotype class
Patients in 3billion (%)

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