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CLPTM1L

Synonyms
CRR9
External resources
Summary
The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,122
Likely benign
3,391
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CLPTM1L gene.

Phenotype class
Patients in 3billion (%)

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