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CLEC10A

Synonyms
CD301, CLECSF13, CLECSF14, HML, HML2, MGL
External resources
Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,923
Likely benign
1,389
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CLEC10A gene.

Phenotype class
Patients in 3billion (%)

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