Home > Gene Browser > BCL2L14

BCL2L14

Synonyms
BCLG
External resources
Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,036
Likely benign
892
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on BCL2L14 gene.

Phenotype class
Patients in 3billion (%)

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