Home > Gene Browser > ARHGAP27

ARHGAP27

Synonyms
CAMGAP1, PP905, SH3D20, SH3P20
External resources
Summary
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,883
Likely benign
2,027
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ARHGAP27 gene.

Phenotype class
Patients in 3billion (%)

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