About Duchenne & Becker Muscular Dystrophy

Duchenne and becker muscular dystrophy related DMD gene is located on the X chromosome.
Muscular dystrophy is a group of diseases which cause progressive weakness and loss of muscle mass. Duchenne muscular dystrophy and Becker muscular dystrophy are two different diseases, but are often paired due to similarity.

Duchenne & Becker muscular dystrophy is a rare genetic disorder caused by a defective DMD gene on the X chromosome, affecting our body's skeletal muscles.

Prevalence / Onset

Map background with the silhouettes of a baby and a child and texts saying "Duchenne and becker muscular dystrophy affects 1.4 out of 10,000 males aged 5 to 24 years."


Duchenne & Becker muscular dystrophy, combined, affects 1.4 out of 10,000 males aged 5-24.

Duchenne muscular dystrophy is three times more prevalent than Becker muscular dystrophy.


Duchenne muscular dystrophy's symptoms usually appear early in childhood.
Becker muscular dystrophy's symptoms usually appear later in childhood or adolescence.


Nine symptoms: Frequent falls, Difficulty rising from a lying or sitting position, Trouble running and jumping, Waddling gait, Walking on the toes, Large calf muscles, Muscle pain and stiffness, Learning disabilities, and Delayed growth
The two muscular dystrophies express similar symptoms, but Duchenne muscular dystrophy develops symptoms more severe in nature, at a faster rate.

Inheritance Pattern

A family tree showing the X-linked recessive inheritance pattern of duchenne and becker muscular dystrophy.
Duchenne & Becker muscular dystrophy's inerhitance pattern is X-linked recessive.

Although primarily found in males, females may also have mild symptoms.


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  2. Medications
    Prednisone and deflazacort (Emflaza®) can slow down the loss of muscle strength.
    Eteplirsen (Exondys 51 - FDA approved) and golodirsen (Vyondys 53 - FDA approved) can treat some of the patients with Duchenne muscular dystrophy.

    Range-of-motion and stretching exercises can help to keep your joints flexible.
    Braces and Mobility aids can help you to self-support and maintain mobility.
    Breathing assistance can be used for better oxygen delivery. A sleep apnea device can be helpful during the night, or a ventilator can be needed for some patients.

    Spine surgery can be needed to treat spinal curvature, which could make breathing difficult.

Living with Duchenne & Becker Muscular Dystrophy

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  2. Exercise
    Aerobic exercises like swimming and walking can help maintain muscle strength. |
    Before attempting such, consult with a doctor to make sure certain exercises are right for you.

    Regularly Get Lungs & Heart Checked
    It is recommended to undergo regular checkups to prevent complications from muscular dystrophy.

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